
Arsenal Suffer Huge Injury Blow as William Saliba Is Forced Out of Liverpool Clash with Knock Just Minutes into Anfield Duel
Early Setback Stuns the Gunners at Anfield
In football, timing can be everything. Unfortunately for Arsenal, the clock ticked barely four minutes at Anfield before disaster struck. Star defender William Saliba, the cornerstone of Mikel Arteta’s backline, was forced off the pitch after sustaining a knock that left him unable to continue.
The Frenchman’s early withdrawal left Arsenal fans stunned and left his manager with an unenviable reshuffle against the reigning Premier League champions. New signing Cristhian Mosquera stepped in to fill the void, making just his second appearance since his summer arrival from Valencia.
For a game billed as a heavyweight showdown between two title hopefuls, Arsenal’s evening began with a gut punch that set the tone for a tense, unpredictable battle.
What Happened?
Just minutes after kick-off, Saliba pulled up awkwardly following a coming-together with a Liverpool forward. Though he attempted to continue briefly, it was clear he was struggling. Shaking his head, the 23-year-old French international signalled to the bench that he could not continue.
Arteta immediately turned to Mosquera, who only last week made his Gunners debut in the clash against Leeds. The 19-year-old Spaniard was thrust into one of the most intimidating fixtures English football has to offer — away at Anfield, with Mohamed Salah, Darwin Núñez and company lining up across from him.
For Arsenal, losing Saliba so early in the contest was more than a tactical headache. It was a psychological blow too, given the importance of the Frenchman’s calm presence in big games.

Arsenal v Leeds United – Premier League
The Bigger Picture: Arsenal’s Growing Injury Crisis
If Arsenal were hoping for smooth sailing into September, their luck with injuries has made that almost impossible. Saliba’s early exit only adds to an already bruised squad list.
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Martin Ødegaard, the club captain, travelled with the squad to Merseyside but was named among the substitutes. He continues to manage a shoulder injury picked up against Leeds.
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Bukayo Saka, perhaps the team’s most influential attacker, is absent with a hamstring injury that could keep him sidelined for several weeks.
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Kai Havertz is also missing, with a knee problem expected to rule him out for a longer period.
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Defensive depth is already thin, with Ben White also not at full fitness.
Add Saliba to that list, and suddenly Arsenal’s bid to match the firepower of Liverpool feels even more precarious.
Why Saliba Matters So Much
Saliba’s importance to Arsenal cannot be overstated. When fit, he provides not just defensive solidity but also the confidence to play a higher line and dictate the tempo of games.
Last season, when Arsenal’s title charge faltered late in the campaign, much of the blame was linked to Saliba’s injury absence. Without him, the Gunners conceded more goals, lost their composure in defence, and ultimately saw Manchester City surge past them to claim the title.
It’s no exaggeration to say that Saliba has become one of the Premier League’s most indispensable centre-backs. His combination of athleticism, positional awareness, and composure on the ball make him the ideal modern defender. To lose him in the opening minutes of such a high-profile clash is as damaging mentally as it is tactically.
Did You Know?
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Teenage star to defensive rock: Saliba joined Arsenal in 2019 as a teenager from Saint-Étienne but spent time on loan before breaking into the first team. Since then, he has quickly grown into a leader in Arteta’s defensive structure.
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Mosquera’s rise: His replacement, Cristhian Mosquera, joined from Valencia this summer. At 19, he is seen as one of Spain’s brightest defensive prospects. Facing Liverpool at Anfield in only his second game is a baptism of fire few defenders would envy.
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Arsenal’s Anfield struggles: The Gunners have not enjoyed consistent success at Anfield in the Premier League era. Even at their best, it has often been a venue of frustration. Losing Saliba so early only adds to the narrative of hardship in this fixture.
The Immediate Aftermath at Anfield
The substitution reshaped Arsenal’s backline. Mosquera partnered Gabriel Magalhães, with Oleksandr Zinchenko and Takehiro Tomiyasu expected to lend extra defensive cover.
Liverpool, sensing vulnerability, immediately tested the new-look defence. Crosses were aimed at Núñez, Salah looked to isolate Mosquera, and the Kop roared every time Arsenal’s replacement centre-back was forced into a duel.
For Mosquera, this was a chance to prove himself. For Arsenal, it was a nerve-wracking test of depth in a game that could have huge implications for the title race.
The Bigger Picture for the Season
While the focus is on the Anfield clash, the implications of Saliba’s injury could stretch far beyond a single match.
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Impact on Arsenal’s title challenge
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Losing Saka and Saliba at the same time is a nightmare scenario. These are arguably the two most irreplaceable players in Arteta’s system. If Saliba’s knock proves serious, Arsenal’s defensive stability could once again unravel.
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Pressure on new signings
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Mosquera’s arrival was meant to bolster depth, but few expected him to be tested this severely, this soon. Whether he sinks or swims will have a major influence on Arsenal’s autumn fixtures.
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International break timing
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In one sense, the injury comes at a “good” time. With the international break approaching, Arsenal have two weeks to assess and recover. In another sense, though, it robs Saliba of the chance to join France and risks disrupting his rhythm.
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What Next for Saliba?

Liverpool v Arsenal – Premier League
Arsenal’s medical team will now take centre stage. Initial indications suggest the knock is not catastrophic, but until scans are completed, no definitive timeline can be given.
It is already considered unlikely that Saliba will join up with Didier Deschamps’ France squad during the break. That, in itself, may be a blessing in disguise for Arsenal, allowing him to recover fully at London Colney.
For Arteta, the hope will be that this is nothing more than a short-term setback. The nightmare scenario would be a repeat of last season, when Saliba’s prolonged absence coincided with Arsenal’s collapse in the title race.
Conclusion: A Test of Arsenal’s Resilience
Football seasons are defined not just by moments of brilliance but by how teams respond to adversity. For Arsenal, losing William Saliba so early in such a crucial clash is a brutal test of resilience.
The Gunners entered Anfield already carrying injuries to Saka, Havertz, and Ødegaard. To now lose their defensive leader threatens to derail momentum at a critical stage.
And yet, challenges like this can also forge character. Mosquera has a chance to prove he belongs at this level. Gabriel and Zinchenko will be asked to step up. Arteta, as ever, will need to find tactical solutions.
If Arsenal can weather this storm — both at Anfield and in the weeks to come — they may look back on Saliba’s knock not as a defining blow, but as the moment their squad’s true resilience was revealed.
Until then, though, fans will wait anxiously for the medical verdict. Because for Arsenal, the health of William Saliba could very well determine the trajectory of their season.
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